Directly observed therapy for treating tuberculosis

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Directly observed therapy for treating tuberculosis

BACKGROUND Tuberculosis (TB) requires at least six months of treatment. If treatment is incomplete, patients may not be cured and drug resistance may develop. Directly Observed Therapy (DOT) is a specific strategy, endorsed by the World Health Organization, to improve adherence by requiring health workers, community volunteers or family members to observe and record patients taking each dose. ...

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Moving Beyond Directly Observed Therapy for Tuberculosis

1 Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America, 2 Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York, New York, United States of America, 3 Massachusetts General Hospital, Harvard Medical School, Harvard School of...

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Tuberculosis recurrence after directly observed therapy.

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Fostering Directly Observed Treatment in Tuberculosis: A Program Manager’s Perspective

Global Tuberculosis (TB) report (2013) has revealed that an estimated 8.6 million people developed TB of which, India accounts for almost 26% of the cases. These estimates clearly suggest that the country’s efforts to achieve Millennium Development Goal 6 by 2015 have not delivered the desired output. In India, the TB prevention and control activities are supervised and implemented under the Re...

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Caveat emptor? Meta-analysis of studies comparing self-observed therapy and directly observed therapy for tuberculosis.

Pasipanodya and Gumbo compared self-administered therapy (SAT) with directly observed therapy (DOT) to determine the proportion of cases with microbiologic failure, relapse, and acquired drug resistance among a pooled cohort of 12 482 persons with tuberculosis from 10 independent studies [1]. The concept of DOT first emerged as a potential therapeutic alternative to resource-intensive hospitali...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2015

ISSN: 1465-1858

DOI: 10.1002/14651858.cd003343.pub4